The Tiger Milk Mushroom is an important medicinal mushroom in Southeast Asia and has been consumed frequently by the natives as a cure for a variety of illnesses.  The history of usage for tiger milk mushroom dated back to almost 400 years ago. Local Malay and Chinese traditional practitioners have used it to treat leukemia, cervical cancer, intestinal ulcer disease, kidney disease, body swelling, fever, asthma, and consumed as general tonic. In Hong Kong and China, the Tiger milk mushroom is a costly traditional medicine utilized for the treatment of gastric ulcers and liver-related diseases, such as hepatitis and cancer.  Aqueous extract of Tigers milk mushroom contained NGF-like compound/s that enhanced neurite outgrowth activity. 
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 Kong, B.-H., Tan, N.-H., Fung, S.-Y., Pailoor, J., Tan, C.-S., & Ng, S.-T. (2015, October 21). Nutritional composition, antioxidant properties, and toxicology evaluation of the sclerotium of Tiger Milk Mushroom Lignosus tigris cultivar E. Retrieved from https://www.sciencedirect.com/science/article/pii/S0271531715002523
 Shin-Yee Fung, C.-S. T. (1970, January 1). The Bioactivity of Tiger Milk Mushroom: Malaysia’s Prized Medicinal Mushroom. Retrieved from https://link.springer.com/chapter/10.1007/978-981-10-5978-0_5
 Kong, Boon-Hong, Tan, Nget-Hong, Fung, Shin-Yee, & Jayalakshmi. (2016, July 25). Sub-Acute Toxicity Study of Tiger Milk Mushroom Lignosus tigris Chon S. Tan Cultivar E Sclerotium in Sprague Dawley Rats. Retrieved from https://www.frontiersin.org/articles/10.3389/fphar.2016.00246/full
 Eik, Lee-Fang, Naidu, Murali, David, Pamela, … Vikineswary. (2011, December 6). Lignosus rhinocerus (Cooke) Ryvarden: A Medicinal Mushroom That Stimulates Neurite Outgrowth in PC-12 Cells. Retrieved from https://www.hindawi.com/journals/ecam/2012/320308/