Cordyceps ophioglossoides may protect the Aβ-induced neuronal cell death and memory loss through free radical scavenging activity. These results further suggest that Cordyceps ophioglossoides mycelium may be valuable for the protection from Alzheimer’s dementia. The chemical constituents include cordycepin (3′‐deoxyadenosine) and its derivatives, ergosterol, polysaccharides, a glycoprotein and peptides containing α‐aminoisobutyric acid. They include anti‐tumour, anti‐metastatic, immunomodulatory, antioxidant, anti‐inflammatory, insecticidal, antimicrobial, hypolipidaemic, hypoglycaemic, anti‐ageing, neuroprotective and renoprotective effects.[1-2] Polysaccharide accounts for the anti‐inflammatory, antioxidant, anti‐tumour, anti‐metastatic, immunomodulatory, hypoglycaemic, steroidogenic and hypolipidaemic effects. Cordycepin contributes to the anti‐tumour, insecticidal and antibacterial activity. Ergosterol exhibits anti‐tumour and immunomodulatory activity.[3]

*These statements have not been evaluated by the FDA. This information is not intended to diagnose, treat, cure or prevent any disease.


Mushroom research:

[1] Kim. (2004, July 10). Mycelial Extract of Cordyceps ophioglossoides Prevents Neuronal Cell Death and Ameliorates β-Amyloid Peptide-Induced Memory Deficits in Rats. Retrieved from

[2] Ng, T. B., & Wang, H. X. (2010, February 18). Pharmacological actions of Cordyceps, a prized folk medicine. Retrieved from

Md. Asaduzzaman Khan and Mousumi Tania, Cordycepin in Anticancer Research: Molecular Mechanism of Therapeutic Effects, Current Medicinal Chemistry, 10.2174/0929867325666181001105749, 27, 6, (983-996), (2020).

[3] Qinqin XU, Longxian LÜ, Shaoyun CHEN, Jing ZHENG, Gaoli ZHENG and Yongquan LI, Isolation of Cordyceps ophioglossoides L2 from Fruit Body and Optimization of Fermentation Conditions for Its Mycelial Growth, Chinese Journal of Chemical Engineering, 10.1016/S1004-9541(08)60206-2, 17, 2, (278-285), (2009).